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WHAT IS A TREATMENT OPTION FOR OVERACTIVE BLADDER (OAB)?

The sooner you talk with your doctor about your symptoms, the sooner you can discover overactive bladder treatment options that may help

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Behavioral therapies for overactive bladder

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Your doctor may suggest behavioral therapies for OAB treatment

  • Pelvic floor muscle training (“kegels”)
  • Establishing routine timing of bathroom trips
  • Reducing fluid intake (especially at night) and avoiding food and drinks that are considered bladder irritants (for example, alcohol and caffeine)
Assess Your Symptoms

Medications used to treat overactive bladder

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There are 2 main types of prescription treatments available for treating OAB symptoms

  • Beta-3 agonists (β3-agonists) work to lessen OAB symptoms by helping the bladder muscle relax so it can hold more urine
  • Anticholinergics (ACHs) work to lessen OAB symptoms by helping to stop involuntary bladder contractions (the bladder squeezing itself without your control)
How Gemtesa Works

Remember, everyone is unique. No treatment is right for everyone, you may need to try several treatments before finding the one that works for you.

It's important to continue working with your doctor to find the best ways to manage your OAB symptoms.

Have you been dealing with bothersome OAB symptoms? Start a conversation with your doctor so you can discuss your options.

treatment assess symptoms

Before your appointment, try following these lifestyle tips to help with symptoms

  • Stay hydrated
    A total of 6 to 8 glasses of water is still recommended throughout the day
  • Keep moving
    Strength training, aerobic exercise, balance, and flexibility are beneficial for overall health. Pelvic floor exercises can help decrease leakage episodes
  • Lose excess weight
    Losing weight can help reduce leakage episodes. In some cases, women who lost 10% of their body weight reduced their leakage by half
  • Stop smoking
    Coughing causes downward pressure on the bladder, which can lead to leakage. Just another great reason to quit smoking

Avoiding foods that are known bladder irritants may also be helpful

  • Alcohol
  • Carbonated beverages
  • Citrus fruits and juice
  • Corn syrup
  • Spicy foods
  • Milk
  • Tea
  • Vinegar
  • Apples
  • Chocolate
  • Coffee
  • Cranberries
  • Honey
  • Sugar and artificial sweeteners
  • Tomatoes

Hear how Kate felt after her doctor explained her overactive bladder diagnosis and treatment options

At first, I didn't think there was a therapy that would treat my overactive bladder.”

Kate, a real GEMTESA patient who has been compensated for her participation in this video

Transcript

At first, I didn't think there was a therapy that would treat my overactive bladder, OAB, symptoms.”

[Text on screen] More Than My OAB: Kate's GEMTESA Journey

Talking to My Doctor About Overactive Bladder

Kate is a real patient taking GEMTESA who has been compensated by Urovant Sciences for her participation in this video.

Leakage episodes, for me, were a constant concern. They controlled my life 24/7.

 

My first visit with the doctor was amazing. I was able to explain my symptoms, my issues, and it felt great to have someone listen.

 

The doctor explained to me a common occurrence, and that is “key-in-lock” syndrome, and that is the uncontrollable urge to use the bathroom once I got home.

 

Once I put that key in my door lock, then I would flood my pads.

 

After my pelvic exam, the doctor explained to me that I do have OAB symptoms.

 

The doctor explained to me and shared a list of options for me and GEMTESA was one of those options.”

[Text on screen] GEMTESA is a prescription medication for the treatment of overactive bladder (OAB) in adults with symptoms of leakage episodes, urgency, and frequency.

The doctor explained to me that there would be possible side effects and those could include a headache or common cold symptoms.

 

I would recommend if someone is dealing with OAB symptoms that they take that first step and seek a healthcare professional.”

[Text on screen] Side effects may include headache, common cold symptoms, diarrhea, nausea, urinary tract and upper respiratory tract infection. Please see Important Safety Information at the end of this video.

If you're dealing with bothersome OAB symptoms, there's a treatment that may help.

Ask a healthcare professional about GEMTESA today.

Do not take if you have a known allergic reaction to GEMTESA or its ingredients. Tell your doctor right away if you are unable to empty your bladder or if you have a weak urine stream.

[Text on screen] GEMTESA may increase your chances of not being able to empty your bladder.

Tell your doctor if you are taking medicines that contain digoxin, or if you have liver or kidney problems.

Side effects may include headache, common cold symptoms, diarrhea, nausea, urinary tract and upper respiratory tract infection.

[Text on screen] Available by prescription only. Call 1-833-UROVANT.

Full Product Information can be found at GEMTESA.com/PI

Learn how GEMTESA may help with OAB symptoms

 

IMPORTANT SAFETY INFORMATION

CONTRAINDICATIONS

GEMTESA is contraindicated in patients with known hypersensitivity to vibegron or any components of the product.

WARNINGS AND PRECAUTIONS

Urinary Retention

Urinary retention has been reported in patients taking GEMTESA. The risk of urinary retention may be increased in patients with bladder outlet obstruction and also in patients taking muscarinic antagonist medications for the treatment of OAB. Monitor patients for signs and symptoms of urinary retention, particularly in patients with bladder outlet obstruction and patients taking muscarinic antagonist medications for the treatment of OAB. Discontinue GEMTESA in patients who develop urinary retention.

ADVERSE REACTIONS

Most common adverse reactions (2%) reported with GEMTESA were headache, urinary tract infection, nasopharyngitis, diarrhea, nausea, and upper respiratory tract infection.

 

INDICATIONS AND USAGE

GEMTESA® is a beta-3 adrenergic agonist indicated for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults.

IMPORTANT SAFETY INFORMATION

CONTRAINDICATIONS

GEMTESA is contraindicated in patients with known hypersensitivity to vibegron or any components of the product.

WARNINGS AND PRECAUTIONS

Urinary Retention

Urinary retention has been reported in patients taking GEMTESA. The risk of urinary retention may be increased in patients with bladder outlet obstruction and also in patients taking muscarinic antagonist medications for the treatment of OAB. Monitor patients for signs and symptoms of urinary retention, particularly in patients with bladder outlet obstruction and patients taking muscarinic antagonist medications for the treatment of OAB. Discontinue GEMTESA in patients who develop urinary retention.

ADVERSE REACTIONS

Most common adverse reactions (2%) reported with GEMTESA were headache, urinary tract infection, nasopharyngitis, diarrhea, nausea, and upper respiratory tract infection.

Please see full Prescribing Information.

You are encouraged to report side effects and product complaints associated with GEMTESA by calling 1-833-876-8268.

Sumitomo Pharma logo.

is a trademark of Sumitomo Pharma Co., Ltd., used under license. SUMITOMO PHARMA is a trademark of Sumitomo Pharma Co., Ltd., used under license. SUMITOMO is a registered trademark of Sumitomo Chemical Co., Ltd., used under license. Sumitomo Pharma America, Inc. is a U.S. subsidiary of Sumitomo Pharma Co., Ltd.

GEMTESA, and the GEMTESA logo are trademarks of Urovant Sciences GmbH, registered in the U.S. and in other countries.

©2024 Sumitomo Pharma America, Inc. All rights reserved. US-VBGN-2000042 (v9.0) 04/24

IMPORTANT SAFETY INFORMATION

Do not take GEMTESA if you are allergic to vibegron or any of the ingredients in GEMTESA.

Before you take GEMTESA, tell your doctor about all your medical conditions, including if you have liver problems; have kidney problems; have trouble emptying your bladder or you have a weak urine stream; take medicines that contain digoxin; are pregnant or plan to become pregnant (it is not known if GEMTESA will harm your unborn baby; talk to your doctor if you are pregnant or plan to become pregnant); are breastfeeding or plan to breastfeed (it is not known if GEMTESA passes into your breast milk; talk to your doctor about the best way to feed your baby if you take GEMTESA).

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

What are the possible side effects of GEMTESA?
GEMTESA may cause serious side effects including the inability to empty your bladder (urinary retention). GEMTESA may increase your chances of not being able to empty your bladder, especially if you have bladder outlet obstruction or take other medicines for treatment of overactive bladder. Tell your doctor right away if you are unable to empty your bladder.

The most common side effects of GEMTESA include headache, urinary tract infection, nasal congestion, sore throat or runny nose, diarrhea, nausea and upper respiratory tract infection. These are not all the possible side effects of GEMTESA. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see full Prescribing Information.

What is GEMTESA?

GEMTESA is a prescription medicine for adults used to treat the following symptoms due to a condition called overactive bladder:

  • urge urinary incontinence: a strong need to urinate with leaking or wetting accidents
  • urgency: the need to urinate right away
  • frequency: urinating often

It is not known if GEMTESA is safe and effective in children.

IMPORTANT SAFETY INFORMATION

Do not take GEMTESA if you are allergic to vibegron or any of the ingredients in GEMTESA.

Before you take GEMTESA, tell your doctor about all your medical conditions, including if you have liver problems; have kidney problems; have trouble emptying your bladder or you have a weak urine stream; take medicines that contain digoxin; are pregnant or plan to become pregnant (it is not known if GEMTESA will harm your unborn baby; talk to your doctor if you are pregnant or plan to become pregnant); are breastfeeding or plan to breastfeed (it is not known if GEMTESA passes into your breast milk; talk to your doctor about the best way to feed your baby if you take GEMTESA).

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

What are the possible side effects of GEMTESA?
GEMTESA may cause serious side effects including the inability to empty your bladder (urinary retention). GEMTESA may increase your chances of not being able to empty your bladder, especially if you have bladder outlet obstruction or take other medicines for treatment of overactive bladder. Tell your doctor right away if you are unable to empty your bladder.

The most common side effects of GEMTESA include headache, urinary tract infection, nasal congestion, sore throat or runny nose, diarrhea, nausea and upper respiratory tract infection. These are not all the possible side effects of GEMTESA. For more information, ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see full Prescribing Information.

You are encouraged to report side effects and product complaints associated with GEMTESA by calling 1-833-876-8268.

Sumitomo Pharma logo.

is a trademark of Sumitomo Pharma Co., Ltd., used under license. SUMITOMO PHARMA is a trademark of Sumitomo Pharma Co., Ltd., used under license. SUMITOMO is a registered trademark of Sumitomo Chemical Co., Ltd., used under license. Sumitomo Pharma America, Inc. is a U.S. subsidiary of Sumitomo Pharma Co., Ltd.

GEMTESA, and the GEMTESA logo are trademarks of Urovant Sciences GmbH, registered in the U.S. and in other countries.

©2024 Sumitomo Pharma America, Inc. All rights reserved. US-VBGN-2000043 (v10.0) 03/24